Bioproductions

Bioproductions

research program

Biomass, biotechnologies and sustainable technologies for chemistry and fuels.

Headline news

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14 October 2026

By: The B-BEST Team

Focus on microbial electrosynthesis: when bacteria turn our waste into useful molecules

What if the next molecule for making solvents or bioplastics were hidden in wastewater? What if food waste could be turned into pigments for the textile industry? This is the aim of the teams behind the ElectroMIC research project, supported by the PEPR Bioproductions programme, which is exploring a technology capable of combining electricity and microbial activity to transform organic waste into useful molecules.
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13 October 2026

By: The B-BEST Team

Launch of the IBISBA Move & Connect European mobility programme

IBISBA, the European research infrastructure dedicated to industrial biotechnology, and the National Research Programme for Bioproductions (PEPR Bioproductions) are launching a mobility programme between French and European research infrastructures.
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22 September 2026

By: B-BEST team

[VIDEOS] PEPR B-BEST PhD students present their theses in 180 seconds

Ten PhD students from the PEPR B-BEST programme took part in the “My PhD in 180 seconds” session, held during the Annual Conference from 24 to 26 June 2026 in Marseille. Watch the videos of their presentations now, along with the illustrations created live, each representing a different PhD thesis.
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22 May 2026

By: B-BEST

Policy brief on biotechnology

The PEPR B-BEST is actively involved in policy discussions, particularly at European level.

17 July 2026

By: B-BEST

From biomass to bio-based products

Want to better understand biomass and bio-based products? Here is an overview of the issues and applications.
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08 October 2026

By: The B-BEST Team

A closer look at advanced biofuels

What do straw, seaweed and used cooking oil have in common? Answer: they can all be turned into biofuels! To mark the Fête de la Science, IFPEN presented its work on producing biofuels from non-food resources at the Musée des Arts et Métiers in Paris.

The ROSALIND project, winner of the 2024 call for proposals, is developing new approaches to valorise lignin – a plant-based polymer that remains largely under-utilised – to produce polyphenolic molecules of interest to the chemical industry.

From 6 to 10 July 2026, the MAMABIO project (Machine Learning Methodology for Accelerated and Predictive Atom-Scale Simulation of the Transformation of Bio-based Molecules), a targeted project under the PEPR B-BEST programme, took part in the 20th International Conference on Theoretical Aspects of Catalysis (ICTAC 20) in Delft (Netherlands).

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From 24 to 26 June 2026, the B-BEST community gathered in Marseille for three days of discussion, networking and knowledge-sharing on biotechnology, sustainable chemistry and bio-based products that will help tackle the challenges of the future. Around 135 people took part in the event.

The programme's projects

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15 December 2025

By: B-BEST

FillingGaps

Biomass at all scales to understand its properties.
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17 January 2025

By: B-BEST

Applestorm

Imaging biomass multiscale architecture.
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17 January 2025

By: B-BEST

MICRO-MASS

Combining biocatalysts and metal supported catalysts for valorizing lignin to aromatic aldehydes in an integrated process.
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17 January 2025

By: B-BEST

WallMat

Biosourced materials inspired from the plant cell walls.
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11 February 2026

By: B-BEST

Nano2BioReact

Establishing relationships between the nanoscale chemical properties of plant cell walls and their impact on biomass reactivity
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08 January 2025

By: B-BEST

Nanomachines

Multi-enzyme nanomachines for controlled transformation of terrestrial plant biomass.
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08 January 2025

By: B-BEST

Tbox4BioProd

Innovative tools for optimizing resource allocation in unicellular and multicellular bioproduction systems.
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08 January 2025

By: B-BEST

Collimator

Controlling metabolic outputs to stabilize and optimize production.
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08 January 2025

By: B-BEST

AlgAdvance

New strategies for developing microalgae as a renewable resource for biofuels.
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08 January 2025

By: B-BEST

BioFUMAC

A new pathway for bio-based acrylic acid through robust fungal production of fumaric acid and engineering of a novel decarboxylase.
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17 January 2025

By: B-BEST

COPE

Chassis Optimization by Proteome-allocation Engineering for diverse bio-production applications.
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17 January 2025

By: B-BEST

Flavosases

Hijacking the Flavobacterium type IX secretion machinery for efficient cellulolytic activity.
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08 January 2025

By: B-BEST

PRODIGES

Process-driven genetic engineering strategies.
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08 January 2025

By: B-BEST

PuLCO

Integrated approach on copper systems to improve recalcitrant polysaccharide utilization.
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11 February 2026

By: B-BEST

CALIBRATE

Combining machine learning and high-throughput immobilisation to predict the stability of catalytic biocomposites for hybrid biorefineries
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11 February 2026

By: B-BEST

REPAROX

Identify and characterise the repair mechanism under oxidative conditions of an iron-sulphur biocatalyst and transpose this mechanism through ab initio design.
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11 February 2026

By: B-BEST

STELLAR

Synthetic cell factories
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08 January 2025

By: B-BEST

OPTISFUEL

New proofs of concept to optimize the production of sustainable fuels.
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08 January 2025

By: B-BEST

FurFun

Functionalization of furan derivatives for the synthesis of bioproducts.
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17 June 2026

By: B-BEST

ElectroMIC

Electrochemically assisted optimization of the metabolic network of microbial communities for organic waste biorefining.
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17 January 2025

By: B-BEST

BioMCat

Combining biocatalysts and metal supported catalysts for valorizing lignin to aromatic aldehydes in an integrated process.
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17 January 2025

By: B-BEST

MALIGNE

Water-soluble enzymatic lignin for high value and sustainable applications.
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17 January 2025

By: B-BEST

PREMIERE LIGNE

Pyrolysis, molecular reconstruction and lignin characterization.
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08 January 2025

By: B-BEST

ROSALIND

Benchmarking of sono- and photocatalysis for lignin demethylation.
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17 January 2025

By: B-BEST

SmartCoupling

Coupling enzymatic and chemistry routes to develop sustainable tools of lignocellulosic biomass transformation into functionalized building blocks.
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17 January 2025

By: B-BEST

WAEster

Environmental biorefinery approach for the production of fatty acid esters and co-products from microalgae cultivated on waste fermentation effluents.
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11 February 2026

By: B-BEST

EXTRAPEC

Enzymatic extraction of pectin-based detergents
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11 February 2026

By: B-BEST

GQD-BIOCAT

Upgrading of bio-based substrates in a single reactor via a hybrid process using graphene quantum dot photocatalysts and biocatalysis
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11 February 2026

By: B-BEST

HEMICELLULOSES

Sustainable integration of chemical and biochemical processes for the recovery of wood hemicellulose
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08 January 2025

By: B-BEST

Galaxy-BioProd

Operational portal for the production of bio-based products.
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08 January 2025

By: B-BEST

AMARETTO

Integration of analytical tools and machine learning to identify markers and predict reactivity of lignocellulosic biomass in enzymatic hydrolysis.
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08 January 2025

By: B-BEST

MAMABIO

Machine learning methodologies for accelerated and predictive atomic-scale simulation of bio-based molecule transformation.
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17 January 2025

By: B-BEST

MuSiHC

Multi-size hybrid cell models.
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25 March 2026

By: B-BEST

BIOCaP-LCA

Integrated modelling of the bioeconomy for consequential and prospective life cycle assessment (LCA)
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11 February 2026

By: B-BEST

SuPRTrYP

Methods for designing yeast consortia to convert non-conventional biomass co-products into tryptophan derivatives
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16 October 2025

By: B-BEST

HEARTS

Human sciences and ethics for the responsible use of technology, towards sustainable bioengineering
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16 October 2025

By: B-BEST

BIOCOSPHERE

Biomass and critical co-dependence between the environmental, economic and social spheres
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16 October 2025

By: B-BEST

GOPARTBIOECO

To a collaborative governance of the bioeconomy research
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16 October 2025

By: B-BEST

PANGOLIN

Perceived relevance of biotechnologies for circular and non-circular bioeconomy products
24 06
From 24 June 2026 to 26 June 2026 Villages Clubs du Soleil - Marseille

PEPR Bioproductions 2026 Annual Conference

Scientific publications

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29 September 2026

By: B-BEST

Scientific publications

Access the HAL platform to submit or view publications resulting from PEPR scientific research.

Videos

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01 October 2026

By: The B-BEST Team

Canal U channel of the French Bioproductions research programme

Find the videos (webinar replays, ‘My thesis in 180 seconds’, etc.) on the Canal U channel of the French Bioproductions research programme.

Scientific results

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13 May 2026

By: B-BEST

Enzymatic wood degradation: a quantitative approach at the cellular level

The research team behind the FillingGaps project, led by Gabriel Paës (INRAE), recently published the results of a study aimed at observing wood undergoing controlled decomposition at the cellular level in the journal New Biotechnology (https://doi.org/10.1016/j.nbt.2025.04.001).
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19 December 2024

By: B-BEST

MAMABIO: A Scientific Breakthrough in Biomass Transformation

The MAMABIO project team, led by Céline Chizallet (IFPEN), has overcome a key hurdle in developing predictive models essential for optimizing biomass transformation processes. This advancement marks a crucial turning point in the design of more efficient processes, paving the way for new opportunities in the energy sector and the production of bio-based chemical molecules.
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19 December 2024

By: B-BEST

Galaxy-BioProd: artificial intelligence invests in the field of retro-biosynthesis: a state of the art

The team behind the Galaxy-BioProd project, led by Jean-Loup Faulon (INRAE), conducted an analysis of scientific literature, shedding light on the latest advances in the use of artificial intelligence for the design of retro-biosynthetic methods. This state of the art, published in ACS Synthetic Biology, reveals a significant source of opportunities for developing innovative and sustainable solutions.