SuPRTrYP

Winning project of the 2025 call for projects.

OBJECTIVE

The SuPRTrYP project aims to develop sustainable biotechnological alternatives to petrochemical synthesis for the production of high-value metabolites such as melatonin, serotonin, and indolic compounds.

APPROACH

SuPRTrYP combines computational and experimental approaches to harness yeast biodiversity and convert agri-food by-products through fermentation. The project relies on:

• The analysis of thousands of yeast genomes to predict optimal metabolite producers
• The development of fermentation processes using residual biomass
• A use case focused on grape and wine by-products rich in tryptophan

A life cycle assessment will quantify the environmental benefits of biotechnological pathways.

IMPACT

SuPRTrYP aims to build an end-to-end value chain, from microbial biodiversity exploration to waste-to-value conversion into health-related compounds, while delivering generic and transferable methods for broader applications.

Project duration:
2026 - 2030

Scientific supervisor:
Anne SIEGEL (CNRS)

Partner institutions