A look back at the ‘Digital tools to accelerate bioproduction’ day

On 18 November, the research axis dedicated to cross-disciplinary methodologies and tools within the PEPR Bioproductions programme organised a day of discussions in Paris on the methods, models and platforms that are currently transforming biotechnology. Several projects presented the tools they use or are developing as part of the programme, with the aim of identifying those that could be used by other projects.

This focus addresses two major challenges:

  • Inventorying, standardising and making experimental resources accessible in order to facilitate the exchange of software and data and reduce development costs.
  • Exploiting experimental data through machine learning to build accurate predictive models — an essential lever for understanding the reactivity and transformation of biomass and optimising processes.

The day highlighted the progress made in this work, with:

  • Spectral data processing and analysis
  • Machine learning-based potentials to optimise atomistic simulations for calculating reaction rates
  • Prediction models for biomass enzymatic hydrolysis reactivity
  • Mechanistic models and hybrid machine learning/mechanistic models
  • Development of tools for standardising experimental protocols for data FAIRisation
  • Tools for engineering microbial strains for bioproduction
  • Reverse engineering of molecular representation
  • Bioreactor modelling

A big thank you to all the speakers and participants for the quality of the discussions and the collective dynamic!

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