Collimator

In the rise of biotechnological production, the unstable production capacities of microorganisms still present serious challenges. Complex genetic regulations of natural or synthetic pathways in microorganisms can ensure complete control of cellular homeostasis and should, theoretically, enhance biological production. To achieve this, it will be necessary to design autonomous, assisted, or user-controlled gene regulation for microbial metabolism in bioreactors, and to integrate their use with technologies capable of providing data on cellular or species-specific parameters within bioreactors.

Project objectives

Design:

Design autonomous, assisted, or user-controlled gene regulation for microbial metabolism in bioreactors.

Construction:

Build various types of sensors capable of providing data on cellular or species-specific parameters.

Control:

Real-time control of the metabolic orientations of microorganisms with external triggers usable in industrial bioreactors.
 

Project lifetime:
 

March 2023 - February 2028

Scientific manager:
 

Gilles Truan (INSA Toulouse)

The consortium:
 

Higher education establishments

Research institutes